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Oncology & Cancer news
Oncology & Cancer
Mutations in noncoding DNA become functional in some cancer-driving genes
Some genes are known to drive cancer, and astonishing new research shows why: Mutations in the noncoding regions become functional, altering the abundance of messenger RNA, or mRNA, and potentially facilitating cell proliferation. ...
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Oncology & Cancer
AI tool predicts responses to cancer therapy using information from each cell of the tumor
With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting. Most of the focus has been on developing genetic sequencing assays or analyses ...
10 hours ago
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New urine-based test detects high-grade prostate cancer, helping men avoid unnecessary biopsies
Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based test that addresses a major problem in prostate cancer: how to separate the slow-growing form of the disease unlikely to cause ...
4 hours ago
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Potential new treatment strategy for aggressive leukemia
Scientists have found a potential treatment strategy for an aggressive type of leukemia by targeting enzymes used by cells to sense and adapt to oxygen levels.
5 hours ago
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Trial for immunotherapy drug shows promise for aggressive breast cancer
University of Hawaiʻi Cancer Center researchers have conducted a phase II clinical trial investigating the potential of pembrolizumab maintenance therapy, a type of immunotherapy, in aggressive forms of breast cancer. The ...
1 hour ago
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Researchers identify patterns that predict ovarian cancer relapse
Using spatial analysis of tissue samples, Cedars-Sinai investigators have identified patterns that could predict whether patients with the most common type of ovarian cancer will experience early relapse after treatment. ...
5 hours ago
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Study finds lower relapse risk in triple-negative breast cancer with high immune cell levels
Women with triple-negative breast cancer, and high levels of immune cells in the tumors, have a lower relapse risk after surgery, even without chemotherapy, according to a recent study published in JAMA.
22 hours ago
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New trial shows immunotherapy post-surgery improves overall survival for kidney cancer
For the first time in fifty years, results from a Phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.
22 hours ago
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Shape-shifting cancer cell discovery reveals potential skin cancer drug targets
Cancer cells can change shape to travel around the body and spread (metastasize), but how they know when to do this has remained elusive.
Apr 17, 2024
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Targeted therapies outperform hundreds of other drugs in 'priming' lung cancer cells for destruction
Through millions of years of evolutionary refinement, the human body has developed a sophisticated surveillance mechanism—the immune system. This intricate network is constantly scanning the body for invaders such as bacteria, ...
Apr 17, 2024
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Adding chemotherapy to hormone therapy helps control locally advanced prostate cancer, finds study
For patients with locally advanced prostate cancer, combined treatment with chemotherapy and hormonal therapy offers extended control of prostate-specific antigen (PSA) levels, compared to hormonal therapy alone, according ...
Apr 17, 2024
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Healthy diet lowers heart disease risk in breast cancer survivors, study finds
A new paper in JNCI Cancer Spectrum finds that following a healthy diet lowers the risk of cardiovascular disease in breast cancer survivors.
Apr 17, 2024
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Antibiotics reveal a new way to fight cancer
Cancer cells grow and spread by hiding from the body's immune system. Immunotherapy allows the immune system to find and attack hidden cancer cells, helping cancer patients live longer lives. However, many patients get little ...
Apr 16, 2024
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A urine-based test that detects tumor DNA fragments could offer early reliable screening for head and neck cancer
Researchers from the University of Michigan Health Rogel Cancer Center have created a urine-based test that detects pieces of DNA fragments released by head and neck tumors. The test could potentially facilitate early detection ...
Apr 16, 2024
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An effective drug delivery system for next-generation treatments to hitch a ride in cancer cells
Antisense oligonucleotides (ASOs) are next-generation drugs that can treat disease by blocking the transfer of harmful messages from our genes. In people with cancer, ASOs have the potential to block messages that encourage ...
Apr 16, 2024
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New insights could unlock immunotherapy for rare, deadly eye cancer
New research from the University of Pittsburgh explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before ...
Apr 16, 2024
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New findings illustrate pathway for screening high-risk individuals for pancreatic cancer
New research in the April 2024 issue of Journal of the National Comprehensive Cancer Network showcases the feasibility of improving early detection and prevention for pancreatic cancer. Global incidences of pancreatic cancer ...
Apr 16, 2024
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Risk for second primary breast cancer low in certain young breast cancer patients
Young breast cancer (BC) survivors (40 years or younger) without a pathogenic variant (PV) have a low risk for developing second primary BC (SPBC), according to a study published online April 11 in JAMA Oncology.
Apr 16, 2024
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Using machine learning to identify patients with cancer that would benefit from immunotherapy
A new study examines the development of two machine learning models to classify the immunophenotype of a cancer specimen.
Apr 16, 2024
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Q&A: When will patients see personalized cancer vaccines?
Catherine Wu has been a pioneer in a promising approach to fight cancer: vaccines that target specific immune-stimulating molecules, known as immunogenic peptides, generated by the distinct genetic mutations of any individual ...
Apr 16, 2024
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