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Immunology news
Immunology
Identifying a new liver defender: The role of resident macrophages
Osaka University researchers have discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier ...
10 hours ago
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Immunology
How immune cells communicate to fight viruses: New mouse model enables identification of chemokine producers and sensors
Chemokines are signaling proteins that orchestrate the interaction of immune cells against pathogens and tumors. To understand this complex network, various techniques have been developed to identify chemokine-producing cells.
9 hours ago
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CD7 CAR T-cell therapy, stem-cell transplant beneficial for CD7-positive tumors
For patients with relapsed or refractory CD7-positive leukemia or lymphoma, sequential CD7 chimeric antigen receptor (CAR) T-cell therapy followed by haploidentical hematopoietic stem-cell transplantation (HSCT) is safe and ...
8 hours ago
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Scientists team up to expand vaccine science's role in the fight against MRSA and other infections
Driven by the overuse of antimicrobials, pathogens are quickly building up resistances to once-successful treatments. It's estimated that antimicrobial-resistant infections killed more than 1 million people worldwide in 2019, ...
Apr 24, 2024
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Immune cells on standby are constantly stimulated by healthy tissue, new study finds
When pathogens invade the body, the immune system must react immediately to prevent or contain an infection. But how do our defense cells stay ready when no attacker is in sight?
Apr 24, 2024
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Newly discovered mechanism helps tumor cells evade the immune system early on
Tumors actively prevent the formation of immune responses by cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München ...
Apr 24, 2024
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CAR T cell therapy targeting HER2 antigen shows promise against advanced sarcoma in clinical trial
Researchers at Texas Children's Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children's Hospital and Houston Methodist have published results of a Phase I clinical trial of a ...
Apr 24, 2024
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Unveiling immune features of heart failure paves the way for targeted therapies
In a recent study published in the Science Bulletin, researchers comprehensively examined the composition and phenotypic features of myeloid cells in human failing hearts at a single-cell level, offering valuable insights ...
Apr 24, 2024
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Allergies can make you miserable. Here's how to track pollen levels near you
Allergy season can bring misery to tens of millions of Americans each year.
Apr 24, 2024
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Researchers identify a cause of immunodeficiency after stroke and heart attack
Every year, between 250,000 and 300,000 people in Germany suffer from a stroke or heart attack. These patients suffer immune disturbances and are very frequently susceptible to life-threatening bacterial infections. Until ...
Apr 23, 2024
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How B cells recognize new variants of SARS-CoV-2
B cells are part of the immune system's memory. Their memories of previous infections or vaccinations provide the template for antibodies that have a protective effect the next time they come into contact with a pathogen.
Apr 23, 2024
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Swimming short fibrous nasal drops achieve intraventricular administration
Adequate drug delivery across the blood-brain barrier is a critical factor in treating central nervous system (CNS) disorders. Inspired by swimming fish and the microstructure of the nasal cavity, Prof. Cui is the first to ...
Apr 23, 2024
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Bacteria in the intestine that change in response to inflammation could have an impact on our immune system
Gut bacteria have emerged as a focal point of scientific exploration, with their intricate roles in our metabolism, nutrition, and overall health coming into sharp focus. New research from the Technion—Israel Institute ...
Apr 22, 2024
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Improving cancer immunotherapy by prolonging T-cell survival
In the past decade, immunotherapy has emerged as the fourth pillar of cancer treatment, joining surgery, radiotherapy and chemotherapy. It is an approved treatment for 15 cancers, including melanoma and some types of lymphomas ...
Apr 22, 2024
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Hitchhiking of synthetic antigen stimulates antibody production against cancer cells
Researchers at the Indian Institute of Science (IISc) have designed a synthetic compound (antigen) that can latch on to a protein in blood and hitchhike a ride to the lymph node, where it can boost the production of antibodies ...
Apr 22, 2024
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Genetically engineering a treatment for incurable brain tumors
Purdue University researchers are developing and validating a patent-pending treatment for incurable glioblastoma brain tumors. Glioblastomas are almost always lethal with a median survival time of 14 months. Traditional ...
Apr 22, 2024
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Researchers identify connection between air pollutants and allergic diseases
A study by researchers at National Jewish Health published in the Annals of Allergy, Asthma & Immunology reports that air pollutants—including particulate matter, pollen, greenhouse gases, and other harmful substances—can ...
Apr 22, 2024
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Review highlights the potential and promise of CAR-T cell therapy in autoimmune diseases
Autoimmune disease (AID) refers to the condition in which the immune system identifies the body's own cells and tissues as foreign, resulting in systemic inflammation. The immune system's self-attack via autoreactive B and ...
Apr 22, 2024
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Researchers develop a new way to safely boost immune cells to fight cancer
Last year alone, more than 600,000 people in the United States died from cancer, according to the American Cancer Society. The relentless pursuit of understanding this complex disease has shaped medical progress in developing ...
Apr 19, 2024
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Signs of multiple sclerosis show up in blood years before symptoms, study finds
In a discovery that could hasten treatment for patients with multiple sclerosis (MS), UC San Francisco scientists have discovered a harbinger in the blood of some people who later went on to develop the disease.
Apr 19, 2024
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