Oncology & Cancer

Targeting cancer's hidden master regulators

Cancer research has long focused on targeting the genetic mutations that drive tumors. Many of these genetic changes affect genes that allow mutated cells to replicate out of control. While developing drugs to target these ...

Medical research

Researchers grow 'synthetic' embryo with brain and beating heart

Researchers from the University of Cambridge have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body—a new avenue for recreating the first ...

Oncology & Cancer

Research sheds new light on pancreatic cancer metastasis

With an overall survival rate of 9% for those diagnosed, pancreatic cancer remains exceedingly difficult to treat. However, the patient's primary tumor typically isn't what leads to death—it is the cancer's ability to evade ...

Oncology & Cancer

Big data analysis finds cancer's key vulnerabilities

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, ...

Oncology & Cancer

Targeting the engine room of the cancer cell

Researchers at Columbia University Irving Medical Center (CUIMC) have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug ...

Cardiology

Mending broken hearts with cardiomyocyte molds

2.5 billion. That's approximately the number of times the human heart beats in 70 years. And sometimes during the course of its unrelenting contractions and relaxations, the heart muscle can no longer bear the strain.

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