Diseases, Conditions, Syndromes

iPSC-derived kidney organoids to model a lifelong renal disease

Researchers have generated induced pluripotent stem cell (iPSC)-derived kidney organoids to model Alport syndrome caused by a mutation in the COL4A5 gene and have demonstrated the utility of a chemical chaperone to rescue ...

Genetics

DOT1L gene variants associated with a new neurological disorder

A study from the laboratory of Dr. Hugo J. Bellen, a distinguished service professor at Baylor College of Medicine and a principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas ...

Genetics

Study weighs in on fears that COVID drug could spawn super virus

COVID-19 patients are often prescribed antiviral drugs that work by reducing the number of viral particles circulating in the body. One such drug, molnupiravir, tricks the virus into generating mutations, some of which are ...

Genetics

Scientists develop new model for understanding uterine fibroids

Northwestern Medicine scientists have developed a new cellular model of uterine fibroids that stem from common genetic mutations, which will accelerate further research and development of future treatments, according to findings ...

Genetics

Researchers reverse hearing loss in mice

New research from The Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has successfully reversed hearing loss in mice.

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