A team of researchers led by Dr. Sandra Castillo and Dr. Mariona Graupera, from the Josep Carreras Leukaemia Research Institute and CIBERONC, have found the AKT inhibitor miransertib could be a new, effective molecular treatment ...
Jun 14, 2022
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A new class of cancer drugs just now entering the marketplace seems promising so far, but researchers at the University of Illinois at Chicago urge doctors to take into account a patient's weight and liver status before prescribing ...
Jul 2, 2019
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Tobacco use causes a field of precancerous cells, increasing the risk of developing head & neck cancer. But exactly how this precancerous field influences cancer has been often overlooked. Now a University of Colorado Cancer ...
Apr 1, 2019
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Dr. Lewis Cantley hasn't eaten sugar in decades. "I have a very simple rule," he says. "I eat fruit, but I don't eat anything that has sugar added to it. And I guarantee everybody would be better off if they ate zero sugar."
Mar 20, 2019
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A very low carbohydrate, high-fat diet called the ketogenic diet may improve the effectiveness of an emerging class of cancer drugs, according to a study in mice by investigators at Weill Cornell Medicine, Columbia University ...
Jul 5, 2018
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More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells—known as the PI3 kinase (PI3K) pathway—but efforts to develop therapies targeting this pathway have ...
Jun 25, 2018
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The combination of taselisib and fulvestrant has shown to slow the growth of cancer in post-menopausal women with estrogen receptor (ER)-positive, human epidermal growth factor receptor-2 (HER2) negative, PIK3CA-mutant, inoperable, ...
Jun 4, 2018
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A research collaboration has led to a new potential treatment for hereditary hemorrhagic telangiectasia (HHT) or Rendu-Osler syndrome, a rare disease that affects blood vessels and was previously untreatable. The study, published ...
Apr 27, 2018
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A multi-institutional research team has identified what may be a novel mechanism underlying acquired resistance to CDK 4/6 inhibitor treatment for breast cancer. In their report published in the Annals of Oncology, the team—led ...
Apr 11, 2018
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The structure of proteins that protect telomeres (shelterin proteins, from "protective shield") are promising targets to combat cancer, but to date, there has been no effective form for attacking them. In the absence of drugs ...
Nov 3, 2017
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