Mutations in the SCN3A gene cause a spectrum of neurological conditions collectively referred to as SCN3A-related neurodevelopmental disorders, which includes different types of epilepsy and brain malformations.
Nov 21, 2023
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Researchers at NYU College of Dentistry's Pain Research Center have developed a gene therapy that treats chronic pain by indirectly regulating a specific sodium ion channel, according to a new study published in the Proceedings ...
Jul 27, 2023
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The gold standard test for predicting the onset of diabetic kidney disease is the albuminuria test. However, detecting albuminuria alone has limited sensitivity and specificity in end-stage renal failure with a decreased ...
Jun 13, 2023
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The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another molecular cause for ...
Feb 13, 2023
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People with chronic epilepsy often experience impaired memory. Researchers at the University of Bonn have now found a mechanism in mice that could explain these deficits. The German Center for Neurodegenerative Diseases (DZNE) ...
Dec 19, 2022
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Therapeutically targeting ion channels in nociceptor neurons may be a promising strategy to manage osteoarthritis pain, according to a Northwestern Medicine study published in Cell Reports.
Oct 5, 2022
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In recent years, cannabidiol, a compound derived from cannabis plants, has begun popping up more and more in everyday life. Now legal in most U.S. states, the cannabinoid commonly known as CBD can be found in supermarkets ...
Jul 15, 2022
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Abnormalities in the proteins responsible for transmitting electrical signals in the heart likely cause abnormal heart rhythms in patients with Duchenne muscular dystrophy (DMD), shows a study published in eLife.
Jun 28, 2022
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The human brain has about as many neurons as glial cells. These are divided into four major groups: the microglia, the astrocytes, the NG2 glial cells, and the oligodendrocytes. Oligodendrocytes function primarily as a type ...
Jan 19, 2021
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Scientists from the MIPT Research Center for Molecular Mechanisms of Aging and Age-Related Diseases have joined forces with their colleagues from Jülich Research Center, Germany, and uncovered how sodium ions drive glutamate ...
Dec 21, 2020
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