A new study from the Department of Neuroscience at Karolinska Institutet characterizes a novel neuronal population in the basal ganglia, responsible for the interaction between two types of neurotransmitters, GABA and acetylcholine. ...
May 26, 2022
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Scientists at Scripps Research have clarified the workings of a mysterious protein called Gαo, which is one of the most abundant proteins in the brain and, when mutated, causes severe movement disorders.
Feb 3, 2021
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Huntington's disease is a fatal inherited disorder that strikes most often in middle age with mood disturbances, uncontrollable limb movements, and cognitive decline. Years before symptom onset, brain imaging shows degeneration ...
Dec 11, 2020
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The tell-tale tremors of Parkinson's disease emerge from abnormal activity in a brain region crucial for voluntary movement. Using a mouse model of the disease, researchers at the Okinawa Institute of Science and Technology ...
Feb 19, 2019
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If 95 percent of your neighbors are chatty and outgoing, you probably know more about them than the 5 percent who are reclusive and shy. It's similar for neuroscientists who study the striatum, a brain region associated with ...
May 2, 2018
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Using an experimental co-culture approach in which two different types of neurons from a mouse model of Huntington's disease (HD) are grown side-by-side, connecting to form critically impacted circuits, researchers at University ...
Sep 5, 2016
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The junctions between nerve cells responsible for releasing and receiving dopamine in the brain are a surprising mismatch that gives this chemical a strong competitive advantage.
Jun 20, 2016
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Researchers have thus far been unable to define how dopamine influences cocaine reward. A recent report published in Neuron has shown that cocaine administration increases dopamine levels in the striatum, activating a signaling ...
Feb 24, 2016
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Mapping the human brain's network of interconnections, known as the connectome is typically done with help from computational tools because recreating interconnections between different brain regions has been challenging ...
Jun 19, 2015
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Synapse, the name for the signal-receiving site on a neuron, comes from the Greek word for contact. Neuroscientists used to maintain that neurons form one-to-one relationship to contact one another. Yet more researchers are ...
Nov 17, 2014
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