Oncology & Cancer
Genetically engineered bacteria can detect cancer cells in a world-first experiment
As medical technology advances, many diseases could be detected, prevented and cured with cells, rather than pills.
Aug 13, 2023
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News tagged with synthetic dna
Oncology & Cancer
DNA nanotubes deliver therapeutics to glioblastoma tumors
Glioblastoma is widely considered the most aggressive brain cancer. Even with treatment, patient survival rates are low, with most living an average of 15–18 months after diagnosis. Because of the highly diverse characteristics ...
Dec 21, 2021
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Oncology & Cancer
Researchers question whether synthetic dyes pose health risks to your colon and rectum
Early-onset colorectal cancer incidence among the young, defined as those under age 50, has been rising globally since the early 1990s. Rates for colon and rectal cancers are expected to increase by 90% and 124%, respectively, ...
Dec 10, 2021
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Diseases, Conditions, Syndromes
MERS DNA vaccine induces immunity, protects from virus challenge in preclinical model
A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at The Wistar Institute induced potent immune responses and afforded protective efficacy in non-human primate (NHP) models ...
Apr 22, 2021
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Medical research
A new gene therapy strategy, courtesy of Mother Nature
Scientists have developed a new gene-therapy technique by transforming human cells into mass producers of tiny nano-sized particles full of genetic material that has the potential to reverse disease processes.
Dec 17, 2019
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HIV & AIDS
DNA technology as a novel strategy for delivery of anti-HIV antibodies
Scientists at The Wistar Institute applied synthetic DNA-based technology to drive in vivo production of broadly neutralizing anti-HIV antibodies in small and large-animal models, providing proof of concept for a simple and ...
Nov 8, 2019
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Oncology & Cancer
Anticancer immunity through tumor antigen identification and conversion to DNA vaccines
Wistar scientists and collaborators demonstrated the utility of an optimized synthetic DNA vaccine platform for rapidly inducing immunity against unique combinations of tumor neoantigens. These results reveal a direct pathway ...
Jan 24, 2019
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Medical research
Synthetic DNA technology provides a novel strategy for effective delivery of a complex anti-HIV agent
Scientists at The Wistar Institute have applied their synthetic DNA technology to engineer a novel eCD4-Ig anti-HIV agent and to enhance its potency in vivo, providing a new simple strategy for constructing complex therapeutics ...
Sep 4, 2018
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Diseases, Conditions, Syndromes
New method could deliver DNA-based vaccines in pill form
A microscopic corn-and-shrimp cocktail could eventually make DNA-based vaccinations and cancer-treating gene therapies an easier pill to swallow, according to new research from the University of Nebraska-Lincoln.
Apr 11, 2017
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Medical research
Scientists find potential treatment for Friedreich's ataxia
Researchers at UT Southwestern Medical Center have identified synthetic RNA and DNA that reverses the protein deficiency causing Friedreich's ataxia, a neurological disease for which there is currently no cure.
Feb 16, 2016
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