On Jan. 31, aducanumab, a pricey drug approved for treatment of early-stage Alzheimer's disease, was withdrawn from the market. And in early March, the Food and Drug Administration delayed its decision regarding whether to ...
Mar 14, 2024
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Early stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cells and the degeneration of these cells. For most diseases, this selective vulnerability pattern ...
Mar 11, 2024
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The effects of Alzheimer's disease are devastating: not being able to recognize loved ones, losing precious memories, losing the ability to perform simple tasks, suffering through mood swings, and so on. Not only are memory ...
Jan 18, 2024
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With the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease, new ways are needed to determine whether memory loss and thinking problems are due to Alzheimer's ...
Nov 15, 2023
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Diseases that run in families usually have genetic causes. Some are genetic mutations that directly cause the disease if inherited. Others are risk genes that affect the body in a way that increases the chance someone will ...
Sep 15, 2023
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A panel of 48 proteins in the cerebrospinal fluid (CSF 48 panel) complements existing CSF biomarkers for Alzheimer disease (AD), according to a study published in the Sept. 6 issue of Science Translational Medicine.
Sep 8, 2023
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Alzheimer's disease, one of the most common neurodegenerative diseases, leads to progressive loss of memory and autonomy. It is characterized by the accumulation of neurotoxic proteins in the brain, namely amyloid plaques ...
Aug 9, 2023
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A new study by researchers at Case Western Reserve University revealed that the progression of Alzheimer's disease (AD) can be slowed by suppressing a specific protein in the brain that causes corrosion.
Jul 24, 2023
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Two pathologies drive the progression of Alzheimer's disease. Early on, amyloid beta plaques lead the way, but around the time cognitive symptoms arise, tau tangles take over as the driving force and cognition steadily declines. ...
Jul 13, 2023
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A new computational technique that combines genomic and tau PET imaging data promises a more personalized approach for subtyping Alzheimer's disease. Based on a novel clustering framework using sparse canonical correlation ...
Jun 27, 2023
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