A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of ...
Apr 9, 2024
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SYNC-T, an investigational therapy that combines a device-induced vaccination at the tumor site with intratumoral infusion of a multitarget biologic drug led to numerous clinical responses in patients with metastatic castrate-resistant ...
Apr 8, 2024
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The xCT protein, which plays an important role as a transport molecule in cells, could play a part in cancer treatment in the future, researchers at Vrije Universiteit Brussel (VUB) have discovered. Their work is the result ...
Mar 26, 2024
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A study by researchers at the UCLA Health Jonsson Comprehensive Cancer Center suggests that injecting engineered dendritic cells directly into cancerous lung tumors can help promote a stronger immune response, causing more ...
Mar 26, 2024
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Traditionally, therapies combining DNA-damaging agents and STING agonists have shown potential in treating cancer by enhancing immune response and reshaping the tumor microenvironment. However, until now, creating a single ...
Mar 20, 2024
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A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers. The findings, published ...
Mar 12, 2024
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Treatment outcomes for locally advanced rectal cancer (LARC) are less favorable for Hispanic and non-Hispanic Black patients versus non-Hispanic White patients, according to a study published online Feb. 29 in JAMA Network ...
Mar 7, 2024
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The tumor microenvironment (TME) is the ecosystem surrounding a tumor, which usually consists of non-tumoral cells and molecules they produce and release. The interplay between tumor cells and the TME significantly impacts ...
Mar 4, 2024
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When foreign antigens trigger an immune response, T cells respond by proliferating and differentiating into two groups—effector and memory cells. Epigenetic and transcriptional pathways mediate this response, but the cells ...
Feb 28, 2024
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Hepatoblastoma (HB) is the most common liver cancer in children. Researchers and physicians in the field are concerned because in the last decade HB has been rising rapidly worldwide and has seen the most rapid increase among ...
Feb 21, 2024
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