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Alzheimer's disease & dementia news
Alzheimer's disease & dementia
New device improves stem cell generation and chance for accessible Alzheimer's cell therapy
Researchers in Sweden say they have improved on a technique for converting regular skin cells into neural stem cells—an advance that they say helps close the gap for accessible personalized cell-based therapies for Alzheimer's ...
18 hours ago
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Genetics
Genetic association study opens up new treatment avenues for Pick's disease, a rare form of early-onset dementia
Pick's disease, a neurodegenerative disease of unknown genetic origin, is a rare type of frontotemporal dementia that affects people under the age of 65. The condition causes changes in personality, behavior and sometimes ...
19 hours ago
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Alzheimer's drug development pipeline: Positive results, new insight on biomarkers position 2024 as 'learning year'
The world of Alzheimer's treatments is at an inflection point as more potential drugs make their way out of clinical trials.
18 hours ago
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Longest study to date assesses cognitive impairment over time in adults with essential tremor
Essential tremor, a nervous system disorder that causes rhythmic shaking, is one of the most common movement disorders. A new study published in the Annals of Neurology reveals details on the increased risk of mild cognitive ...
Apr 24, 2024
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Brain neurons re-entering the cell cycle age quickly and shift to senescence, particularly in neurodegenerative disease
Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study published April 9 in the open-access journal ...
Apr 23, 2024
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Innovative microscopy demystifies metabolism of Alzheimer's
Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year. This number is expected to triple ...
Apr 23, 2024
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Using AI to improve Alzheimer's treatment through the 'gut-brain axis'
Cleveland Clinic researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease.
Apr 22, 2024
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Study shows how depletion of mitochondria in axons can directly lead to protein accumulation
Researchers from Tokyo Metropolitan University have identified how proteins collect abnormally in neurons, a feature of neurodegenerative diseases like Alzheimer's. The research is published in the journal eLife.
Apr 22, 2024
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Occupations that are cognitively stimulating may be protective against later-life dementia
People with a history of cognitively stimulating occupations during their 30s, 40s, 50s, and 60s had a lower risk of mild cognitive impairment (MCI) and dementia after age 70, according to a new study from Columbia University ...
Apr 20, 2024
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Dementia treatments linked with serious side effects: Study
Several antipsychotic treatments given to patients with dementia have been linked to serious side effects including heart failure, a study published Thursday has found.
Apr 20, 2024
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Geneticists develop world's first bioinformatic tool to identify amyloids consisting of multiple copies of same protein
Scientists from St Petersburg University and the University of Montpellier have developed the first software enabling the prediction of pairs of proteins in amyloid fibrils capable of co-aggregation, i.e. a process by which ...
Apr 19, 2024
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Obesity-induced cognitive decline: Role of brain oxidation and tocotrienols
Obesity has become a pressing worldwide health issue, with rates steadily rising over recent decades. Beyond its well-documented associations with physical health issues, such as cardiovascular disease and diabetes, obesity ...
Apr 18, 2024
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Study links lack of diversity in Alzheimer's disease clinical trials to differences in amyloid levels
It's long been recognized that some of the groups most likely to get dementia, including African Americans and Hispanics, are greatly underrepresented in clinical trials. Now a new USC study shows that people from certain ...
Apr 17, 2024
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How Alzheimer's disease progresses faster in people with Down syndrome
Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age. A new study by researchers at Washington University School of Medicine in St. Louis shows that the disease both starts ...
Apr 17, 2024
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Antipsychotics for dementia linked to more harms than previously acknowledged
Antipsychotic use in people with dementia is associated with elevated risks of a wide range of serious adverse outcomes including stroke, blood clots, heart attack, heart failure, fracture, pneumonia, and acute kidney injury, ...
Apr 17, 2024
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Does using your brain more at work help ward off thinking, memory problems?
The harder your brain works at your job, the less likely you may be to have memory and thinking problems later in life, according to a new study published in the journal Neurology. This study does not prove that stimulating ...
Apr 17, 2024
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Scientists identify cell vulnerability 'fingerprint' related to Parkinson's, Lewy body dementia
A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.
Apr 16, 2024
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Common HIV treatments may aid Alzheimer's disease patients
Alzheimer's disease (AD) currently afflicts nearly seven million people in the U.S. With this number expected to grow to nearly 13 million by 2050, the lack of meaningful therapies represents a major unmet medical need. Scientists ...
Apr 16, 2024
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New mechanism uncovered in early stages of Alzheimer's disease
Alzheimer's disease (AD) remains one of the most challenging and prevalent neurodegenerative disorders, affecting millions of individuals worldwide. In a new study published in Developmental Cell, researchers from the lab ...
Apr 15, 2024
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Researchers say common dementia medication doesn't increase risk of death, life-threatening heart abnormalities
Researchers with McMaster University have found that a commonly prescribed dementia medication doesn't increase the risk of death or certain heart rhythm problems, contrary to past warnings.
Apr 15, 2024
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