Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn's disease. This protein, known as ...
Jan 11, 2024
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Mayo Clinic researchers have unraveled the molecular mechanisms that affect which cells infected with human immunodeficiency virus (HIV) die and which survive, a discovery heralded as a step toward eliminating all HIV-infected ...
Jan 11, 2024
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Vaccines have been reliably and affordably protecting people from diseases worldwide for centuries. Until the COVID-19 pandemic, however, vaccine development was still a long and idiosyncratic process. Traditionally, researchers ...
Jan 5, 2024
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Tremendous progress has been made over the last decade in identifying genes leading to autism spectrum disorders (ASD), especially for those who are severely affected. To date, however, these genetic insights have not translated ...
Dec 18, 2023
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A study, published in the journal Gene Expression and led by Brady Jin-Smith from the Department of Pathology at Tulane University, focuses on ALDHs, a group of key enzymes that catalyze the irreversible oxidation of various ...
Dec 15, 2023
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In a novel study, researchers from the Icahn School of Medicine at Mount Sinai have introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain and loss-of-function variants across the genome.
Dec 14, 2023
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The p53 protein is a tumor suppressor that plays a crucial role in preventing the formation of cancerous cells. But when it mutates and becomes defective in cells, the protein can significantly boost a person's risk of cancer ...
Nov 28, 2023
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The human immunodeficiency virus (HIV) is a formidable pathogen. It mutates rapidly; in fact, estimates suggest that the genetic diversity of HIV in a single person at one point in time is equal to the diversity of influenza ...
Nov 22, 2023
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UCLA researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream—potentially revealing a new pathway ...
Nov 9, 2023
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A team of researchers in China has reported for the first time the live birth of a monkey that contains a high proportion of cells derived from a monkey stem cell line. This "chimeric" monkey is composed of cells that originate ...
Nov 9, 2023
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