Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies. The significance is that prion proteins ...
Aug 17, 2020
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A new study in Nucleic Acids Research, published by Oxford University Press, suggests a possible effective treatment strategy for patients suffering from prion disease.
Aug 10, 2020
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Human prion diseases include Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker disease (GSS). A new study in the open-access journal PLOS Biology reports a significant advance in the development of mouse ...
Jun 9, 2020
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Prions are a class of misfolded proteins that form aggregates called amyloid fibrils. These aggregates are the main culprit behind severe mammalian neurodegenerative diseases like Alzheimer's. What makes them so deadly is ...
Apr 7, 2020
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In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit. Found abundantly in our brain cells, tau is normally a ...
Apr 2, 2020
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A new University of Toronto study sheds light on how protein strains vary in the brains of those affected by progressive neurodegenerative diseases like Parkinson's, suggesting the need for patient-specific medicines.
Dec 4, 2019
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Researchers at the Federal University of Rio de Janeiro (UFRJ), in Brazil, have identified that the interaction between prion proteins and DNA may be behind the formation of protein amyloid aggregates and of the emergence ...
Nov 25, 2019
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There are currently no effective treatments for prion diseases, a family of fatal neurodegenerative conditions caused by accumulations of misfolded copies of a naturally occurring protein. But now, there is finally an effective ...
Nov 6, 2019
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A 5-minute soak in a 40% solution of household bleach decontaminated stainless steel wires coated with chronic wasting disease (CWD) prions, according to a new study by National Institutes of Health scientists. The scientists ...
Oct 4, 2019
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A high degree of uncertainty surrounds the issue of the prion disease risk associated with fertility drugs derived from urine, gonadotropins. Writing in the International Journal of Risk Assessment and Management, a team ...
Aug 8, 2019
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