Oncology & Cancer

Review explores therapeutic targets in tumor microenvironment

The tumor microenvironment (TME) is the ecosystem surrounding a tumor, which usually consists of non-tumoral cells and molecules they produce and release. The interplay between tumor cells and the TME significantly impacts ...

Diseases, Conditions, Syndromes

Common immune response is found to be protective across many diseases

Combined, infection, autoimmunity and cancer account for 4 out of every 10 deaths worldwide, and represent major global health challenges. In a paper in the journal Cell Reports, Institute for Systems Biology (ISB) researchers ...

Medications

How a novel drug pushes the HIV capsid to breaking point

Just over a year ago, the European Union and the US Food and Drug Administration approved a new anti-retroviral drug to treat human immunodeficiency virus (HIV) infections. Lenacapavir is the first drug available to patients ...

Oncology & Cancer

New strategy for safer CAR T cell therapy in lymphomas

In treating aggressive lymphomas and blood cancer (leukemia), chimeric antigen receptor T cells (CAR T cells) are increasingly being used. For this therapy, immune cells are taken from patients and programmed by means of ...

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